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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRK
All Species:
24.85
Human Site:
Y317
Identified Species:
45.56
UniProt:
P42685
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42685
NP_002022.1
505
58254
Y317
R
H
G
S
L
Q
E
Y
L
Q
N
D
T
G
S
Chimpanzee
Pan troglodytes
XP_518702
505
58217
Y317
R
H
G
S
L
Q
E
Y
L
Q
N
D
T
G
S
Rhesus Macaque
Macaca mulatta
XP_001112190
505
58228
Y317
R
H
G
S
L
Q
E
Y
L
Q
S
D
A
G
S
Dog
Lupus familis
XP_539091
505
57709
Y321
R
H
G
S
L
Q
E
Y
L
Q
N
D
A
G
A
Cat
Felis silvestris
Mouse
Mus musculus
Q922K9
512
58825
Y324
R
H
G
S
L
Q
E
Y
L
Q
N
D
G
G
S
Rat
Rattus norvegicus
Q62662
506
58147
Y318
R
H
G
S
L
Q
E
Y
L
Q
N
D
G
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q02977
536
59984
F352
S
Q
G
S
L
L
D
F
L
K
D
G
D
G
R
Frog
Xenopus laevis
P13406
537
60828
F353
S
K
G
S
L
L
D
F
L
K
D
G
E
G
R
Zebra Danio
Brachydanio rerio
XP_695937
480
54879
A297
Y
L
Q
N
D
R
G
A
T
L
R
M
S
D
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V9J3
517
59051
Y331
K
H
G
S
L
L
E
Y
L
Q
A
I
A
G
K
Honey Bee
Apis mellifera
XP_396043
451
51726
K272
L
L
E
Y
L
Q
G
K
G
K
T
L
N
L
Q
Nematode Worm
Caenorhab. elegans
NP_493502
507
57512
T321
L
M
Q
E
N
L
L
T
F
L
Q
R
R
G
R
Sea Urchin
Strong. purpuratus
NP_001135852
530
59779
F345
I
N
G
S
L
L
E
F
L
Q
S
P
K
G
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96.6
80.5
N.A.
88.6
88.3
N.A.
N.A.
48.5
48.4
60.5
N.A.
56.8
51.6
50.4
56.6
Protein Similarity:
100
99.8
98
87.7
N.A.
92.9
93
N.A.
N.A.
64.7
64.2
74
N.A.
73.3
67.1
69.4
70.5
P-Site Identity:
100
100
86.6
86.6
N.A.
93.3
93.3
N.A.
N.A.
33.3
33.3
0
N.A.
60
13.3
6.6
46.6
P-Site Similarity:
100
100
93.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
60
60
20
N.A.
66.6
20
6.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
0
0
8
0
24
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
16
0
0
0
16
47
8
8
0
% D
% Glu:
0
0
8
8
0
0
62
0
0
0
0
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
24
8
0
0
0
0
0
0
% F
% Gly:
0
0
77
0
0
0
16
0
8
0
0
16
16
85
0
% G
% His:
0
54
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
8
8
0
0
0
0
0
8
0
24
0
0
8
0
8
% K
% Leu:
16
16
0
0
85
39
8
0
77
16
0
8
0
8
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
8
0
8
8
0
0
0
0
0
39
0
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% P
% Gln:
0
8
16
0
0
54
0
0
0
62
8
0
0
0
16
% Q
% Arg:
47
0
0
0
0
8
0
0
0
0
8
8
8
0
24
% R
% Ser:
16
0
0
77
0
0
0
0
0
0
16
0
8
0
39
% S
% Thr:
0
0
0
0
0
0
0
8
8
0
8
0
16
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
8
0
0
0
54
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _